… renal clearance and continuous renal replacement therapy on appropriateness of recommended meropenem dosing regimens in critically ill patients with susceptible …

R Burger, M Guidi, V Calpini, F Lamoth… - Journal of …, 2018 - academic.oup.com
… of meropenem in critically ill patients in variable renal function or renal replacement therapy
and assessed the appropriateness of recommended dosing regimens for MIC coverage in …

[HTML][HTML] Population pharmacokinetics of standard-dose meropenem in critically ill patients on continuous renal replacement therapy: a prospective observational trial

D Onichimowski, A Będźkowska, H Ziółkowski… - Pharmacological …, 2020 - Springer
… for potential effects on antibiotic dosing in critically ill patients … used to treat life-threatening
infections in the ICU. According … , as long as you give appropriate credit to the original author(s…

Pharmacokinetics of meropenem during continuous renal replacement therapy in critically ill patients

J Solé Violan, J Ferrer Agüero, B Sádaba, S Sancho… - Critical Care, 2014 - Springer
life-threatening consequences, 10,767 had a moderate … , peripheral vasoconstriction,
increased infection risk and impaired … patients and appropriate utilisation of scarce critical care

The impact of continuous renal replacement therapy on antibiotic pharmacokinetics in critically ill patients

M Fiore, L Peluso, FS Taccone… - Expert Opinion on Drug …, 2021 - Taylor & Francis
infections in critically ill patients undergoing continuous … /or sepsis [Citation9], a life threatening
organ dysfunction caused by a … 30 critically ill patients on meropenem, higher or extended …

[HTML][HTML] The effect of a loading dose of meropenem on outcomes of patients with sepsis treated by continuous renal replacement: study protocol for a randomized …

SQ Ni, WB Teng, YH Fu, W Su, Z Yang, J Cai… - …, 2022 - trialsjournal.biomedcentral.com
… detected at the infection site during meropenem treatment, the … The appropriate alpha value
of primary outcomes in each … can be delayed as critically ill patients are often incapacitated. …

Optimization of meropenem and piperacillin dosing in critically ill patients with septic shock and acute kidney injury requiring continuous renal replacement therapy: a …

M Ulldemolins Gómez - 2017 - diposit.ub.edu
… The impact of septic shock, AKI and CRRT on these … the suitability of current meropenem
and piperacillin dosing … over 30min for the treatment of susceptible bacteria (MIC<2mg/L), while …

Practical considerations for individualizing drug dosing in critically ill adults receiving renal replacement therapy

S Kanji, C Roger, FS Taccone… - … and Drug Therapy, 2023 - Wiley Online Library
… and one on meropenem, suggest that increased dosing for … In critically ill patients with
life-threatening bacterial infections, the … use are early and appropriate empiric therapy.(17) …

A guide to understanding antimicrobial drug dosing in critically ill patients on renal replacement therapy

V Pistolesi, S Morabito, F Di Mario… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… The intermittent administration of meropenem during CVVHDF was associated with
subtherapeutic … Aspergillus infection and can also be used to treat patients with other life-threatening

Antimicrobial dosing concepts and recommendations for critically ill adult patients receiving continuous renal replacement therapy or intermittent hemodialysis

BH Heintz, GR Matzke… - … and Drug Therapy, 2009 - Wiley Online Library
… function often occur in critically ill patients, and delaying the start of appropriatelife-threatening
infections.… Pharmacokinetics of meropenem in critically ill patients with acute renal failure

Recommended antibiotic dosage regimens in critically ill patients with augmented renal clearance: a systematic review

CM Silva, JP Baptista, I Santos, P Martins - International Journal of …, 2022 - Elsevier
… In addition, critically ill patients show a higher risk of infection … and enabling appropriate
attainment of PK/PD targets. … , one of eight studies with meropenem and in the only study with …